Simcyp Grant & Partnership Scheme

The deadline for preliminary applications for the 2015/16 Simcyp Consortium Academic Grant and Partnership Scheme (GPS) has passed.

Overview:

Certara is committed to supporting research at associate Academic Centers of Excellence and not-for-profit institutions. In recent years, we have been proud to contribute to research on an ad-hoc basis in partnership with our Simcyp Consortium academic associates. Following the success of these collaborations, and an increase in interest in matters relating to in vitro – in vivo extrapolation (IVIVE) and mechanistic pharmacokinetics/pharmacodynamics (PK/PD), we are inviting applications for Ph.D. or postdoctoral scholarships on an annual basis.

Eligible academic institutions working in the areas of pharmacokinetics, in vitro-in vivo extrapolation (absorption, distribution, metabolism, elimination and transporters), pediatric pharmacology, PK/PD modeling and pharmacogenetics are invited to submit research proposals. A maximum of £30,000 per annum is available for Ph.D. scholarships up to three years in duration or £50,000 per annum for postdoctoral research up to two years in duration.

Eligible institutions must have valid Simcyp Consortium academic licenses* at the time the applications are reviewed. Additionally, either the Principal Investigator or Research Scientist(s) named on the preliminary GPS application form must have attended a Simcyp Full Workshop or three Focused Workshops within the previous 3 years. Existing Simcyp Simulator users who have previously attended a workshop may attend a Focused Workshop to update their knowledge and meet the workshop attendance requirement.

Those eligible can submit applications up to the number of research licenses held (e.g., two academic research licenses, a maximum of two applications). The purpose of the funding is to endorse research at leading academic institutions and not-for-profit organizations that hold a Simcyp Simulator academic license. Successful proposals will be those that demonstrate the application of the Simcyp Simulator at the institute through performance verification via clinical studies or by gathering in vitro data that informs Simcyp simulations.

Research scientists working on successful projects are also provided the opportunity to undertake a sabbatical at Certara’s Sheffield, UK office to work on the project with the support of the Research and Development team. The costs of this, including travel and accommodation, should be factored into the proposal as extra funding will not be provided. Applications will be reviewed by an internal panel of experts along with representatives from our Simcyp Consortium member companies.

*valid academic license = a license held under the conditions stated in the agreement, which must meet the requirement of all listed users of Simcyp Simulator and associated tutors attending a Simcyp Simulator workshop in the previous three years.

Interested institutions should note the following to check they are eligible:

  • Institutions wishing to apply must have a successful track record in the area of proposed research.
  • Institutions must hold a valid Simcyp Simulator academic license at the time the application is reviewed and work concerning the project cannot be sub-contracted.
  • The Principal Investigator or Research Scientist(s) named on the preliminary GPS application form must have attended a Simcyp Full Workshop or 3 Focused Workshops within the previous 3 years.
  • A maximum of £30,000 per annum is available for Ph.D. scholarships up to three years in duration or £50,000 per annum for postdoctoral research up to two years in duration. Applications requesting amounts above these totals will not be considered.
  • The successful institution is required to sign an agreement which grants Certara an exclusive royalty-free license to the project results generated from the research. Prior to submitting your proposal, please check with your institution contracts department that this is agreeable.

Criteria applications will be assessed on:

  • Scientific merit and feasibility of the proposal (e.g., clear objectives, feasibility of project)
  • Track record of the institution and department (e.g., scientific experience and expertise in proposed area of research)
  • Scientific justification of budget and timeline (e.g., achievability of proposed timeline)
  • The institution's previous utilization of in vitro-in vivo extrapolation techniques will also be taken into account.

The application process is a two-stage submission procedure. The deadline for submission of preliminary proposals for this year has passed. Those selected to submit a full application will be contacted at the beginning of November with a deadline to submit the full application by early December 2015. The proposal selected for funding will be announced the following year.

Previous GPS Winners:

2011 - Flinders University of Adelaide, Australia

2012 - University at Buffalo, The State University of New York

2013 - University of Washington, USA

2014 - University of Manchester, UK