This is a PK 2 compartment IV bolus model with a full variance-covariance (Omega) matrix defined. The model is fit using First Order Conditional Estimation (FOCE). For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.
Attached Files
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NONMEM to NLME Translation PK 2comp IV bolus Full VAR COVAR FOCE.pdf 1.04MB
45 downloads
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2Comp_IV_Bolus_Full_Var_Covar_FOCE.phxproj 1.98MB
22 downloads
