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PK 2 Compartment Mixed Absorption Multiple Dose

NONMEM NLME PML Mixed Abosprtion Multiple Dose

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#1 bwendt@certara.com

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Posted 16 December 2017 - 05:06 PM

This is a PK 2 compartment oral model with mixed absorption and multiple doses.

For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.

 

 

Attached File  NONMEM_NLME_TRANSLATION_PK 2 Comp MixedAbsorption_MultipleDose.pdf   1.53MB   91 downloads

 

Attached File  2c_mixabs.phxproj   1.34MB   55 downloads



#2 shekhar.udct@gmail.com

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Posted 14 May 2018 - 12:17 PM

Can Anybody share the phoenix file of this project which can be opened in phoenix 6.4. 



#3 Simon Davis

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Posted 14 May 2018 - 04:12 PM

I don't currently have access to v6.4; it's no longer officially supported. Follow this thread to learn more about Phoenix 8.1 soming next month https://support.certara.com/forums/topic/1100-phoenix-8-is-launching-on-october-3-2017/?p=5246


However the code is discussed in the PDF, but here is the NLME code and also the raw data as a CSV.

Simon.

Attached Files


Edited by Simon Davis, 14 May 2018 - 04:13 PM.


#4 shekhar.udct@gmail.com

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Posted 04 June 2018 - 09:38 AM

Thank you very much Simon..This really helps..

I don't currently have access to v6.4; it's no longer officially supported. Follow this thread to learn more about Phoenix 8.1 soming next month https://support.certara.com/forums/topic/1100-phoenix-8-is-launching-on-october-3-2017/?p=5246


However the code is discussed in the PDF, but here is the NLME code and also the raw data as a CSV.

Simon.



#5 LLLi

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Posted 27 February 2019 - 08:37 PM

Hi Simon,

 

Would you please also post the data set for NONMEM? It was not included in the phxproj file. 

 

Thanks,

LLLi







Also tagged with one or more of these keywords: NONMEM, NLME, PML, Mixed Abosprtion, Multiple Dose

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