This is a PKPD model with 1 compartment IV infusion for PK and an Emax model with baseline, shape factor and effect compartment for PD.
For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.
NONMEM to NLMR Translation 1comp IV infusion Emax Bl_s_Eff.pdf 1.52MB 77 downloads
1Comp_IV_infusion_emax_bl_s_eff.phxproj 1.02MB 41 downloads