This is a PD model, an inhibitory Emax model with baseline and shape factor fitted using FOCE ELS.
For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.
NONMEM to NLME Translation PD Emax_inhibitory_sigmoid.pdf 1.51MB 33 downloads
emax_inh_bl_s.phxproj 1.16MB 22 downloads