Hello All,
I am trying to simultaneously model plasma and tissue PK data from an animal study. While the Pop PK model works ok, no model fit lines are observed for tissue data, for example in IPRED, DV vs. IVAR plots. Model fits are visible for plasma data. Each animal contributes only one time point in the tissue profile. Is that the reason? In that case something should be visible for the DV, PRED vs IVAR plot? I know the model is taking into account all the tissues
as the parameter estimates etc. are obtained and so are CWRES and Pop DV vs Pred, Ipred etc.
Does Phoenix not generate the continuous Pred profile in Pop PK model for animals that have only one time point?
Thanks,
Charvi