Recently, the Chinese guideline for bioequivalence had updated. In BE trials, we would generally get two period for each subject. However, there were some subjects drop out in one of two period. So, these subject would just have one period. This causes the unpaired data. According to the updated guideline in china, these subjects would also be enrolled in BE evaluation, which is different from the previous. In this case, the crossover tool could not be used. Now, how can I conduct nonparametric test for Tmax in Pheonix? If there are other good practices for me to refer? Welcome to discuss follow this topic.