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Simulation results of different dosing

PKPD modeling

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#1 sundar

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Posted 19 June 2019 - 10:44 AM

Hello all, 

 

I request your kind opinion on the following, 

 

I have simulated a PKPD data from lower dose to higher dose, after simulation i am getting the results of time varying concentration with respect to PK. However for PD i am getting the same value through out the time points for each subject. 

 

What could be the possible reason? Is it due to any data mapping issue? 

 

Attached screenshot for your reference. 

 

Thanks for your opinion. 

 

Thanks

Sundar. M 

Attached Files



#2 Simon Davis

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Posted 19 June 2019 - 12:03 PM

HArd to tell from just a screen grab, although I can see a Warnings tab.  would it be possible to post you project?



#3 smouksassi1

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Posted 19 June 2019 - 12:45 PM

we need more info

 

probably a unit or EC50 value problem you seem to have an all or none effect 



#4 sundar

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Posted 19 June 2019 - 04:28 PM

Hi

 

Uploaded the project file for evaluation. 

 

Thanks

Sundar. M 

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