Jump to content


Photo

Minimum number sampling point for AUEC calculation


  • Please log in to reply
2 replies to this topic

#1 sundar

sundar

    Advanced Member

  • Members
  • PipPipPip
  • 36 posts

Posted 12 December 2019 - 11:06 AM

Hello all, 

 

Request your thoughts on minimum number of sampling points requirements for AUEC calculation in Phoenix.

 

Thanks
Sundar. M 



#2 Simon Davis

Simon Davis

    Advanced Member

  • Administrators
  • 1,111 posts

Posted 12 December 2019 - 12:49 PM

i think that really depends on what your effect is and how much you think it is going to change by, and at what rate.

Also will your primary assessment be NCA or will you also try to model the effect curve?

I think you have to have some idea, from literature of similar studies, understanding if a  placebo model is required etc. e.g. we know body temperature, cortisol etc. vary diurnally.

 

 Simon.



#3 sundar

sundar

    Advanced Member

  • Members
  • PipPipPip
  • 36 posts

Posted 13 December 2019 - 04:33 AM

Hi Simon, 

 

Thanks for your reply. 

 

Primary assessment would be based on NCA & PD marker is type I collagen C-telopeptide.

 

I am verifying the adequacy of 4 time points (month 0, 1, 3 & 6) to characterize AUEC

 

Your thought is highly appreciated. 

 

Thanks

Sundar. M






0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users