Looking for some insight in to the below
When running a NCA with multiple dose data, I have a situation where cmax/tmax has not been identified for a particular patient for the final dosing day but AUCtau has been estimated.
The concentration_time data are pretty limited, there is only one non-zero value which occurs ~48 h post dose (the dosing interval is 24 h).
Since cmax/tmax (albeit a single point) occurs outside the dosing interval, I had assumed this is why these parameters were not reported for this patient but what i'm not then understanding is then why an AUCtau is reported (regardless of validity being there is a single non-zero value in this profile).
I fear I am missing something very obvious
[Project file attached, patient in question is B015, Dosing Day 4, Parameter CHOL]
Any help very gratefully received!