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StdError Calculation Method


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#1 Xiuqing Gao

Xiuqing Gao

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Posted 11 October 2021 - 10:38 PM

Hi everyone,

 

I would like to calculate the EC90 StdError using Phoenix modeling, with the sigmoid Emax model (105 in WLN), we are getting the EC50, Emax, and Gamma values and StdError. I used the formula: EC90=(0.9/(1-0.9))**(1/GAMMA)*EC50 to calculate the EC90. 

 

However, does anyone know how the WLN calculate StdError? How can I calculate StdError for EC90? 

 

 

Thanks!

 

Xiuqing



#2 Simon Davis

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Posted 12 October 2021 - 07:13 AM

If you define it as a secondary parameter in your model itself then you will get SEs if it is possible to calculate them, see https://support.cert...-models/?p=4489for an example.






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