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PD response prediction with intial estimate

modeling and simulation

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#1 Ygsla

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Posted 27 July 2022 - 06:49 AM

Hi All,

 

Want to understand if we can predict PD response with available published PK-PD model initial estimate value.

I have PK data and want to predict PD response using literatute established PK-PD model value.

 

Thanks in Advance!!!

YGS

 



#2 bwendt@certara.com

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Posted 27 July 2022 - 07:59 AM

Hi Ygsla,

 

you can rebuild any PK-PD model in Phoenix, this video guides you through all steps:

 

https://www.youtube....h?v=0Hr4UnT07BQ

 

It covers PK model only, but it is straightforward to extend it to the PK-PD case.

 

Bernd


Edited by bwendt@certara.com, 27 July 2022 - 08:00 AM.


#3 Ygsla

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Posted 29 July 2022 - 05:47 AM

Hi Ygsla,

 

you can rebuild any PK-PD model in Phoenix, this video guides you through all steps:

 

https://www.youtube....h?v=0Hr4UnT07BQ

 

It covers PK model only, but it is straightforward to extend it to the PK-PD case.

 

Bernd

Thank you Bernd,







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