HI Folks,
Can we develop PK-PD model with binary reponse data in NLME?
If yes, sharing some more information or suggestion or any built template will be appreciated.
Thanks in advance!!
Regards,
Ygs
Posted 01 August 2022 - 07:11 AM
Hi Ygs, there are some worked examples listed inthe help;
https://onlinehelp.c...imum_Likelihood
e.g. Three category multinomial model with a covariate
Simon
Posted 01 August 2022 - 08:48 AM
Hi Yglsla,
there are also a couple of examples in out PML School (NONMEM-NLME Comparisons):
https://support.cert...rical-response/
Bernd
Posted 10 August 2022 - 08:01 AM
note that phoenix has lot of flexibility and you have multi, ordinal :
https://onlinehelp.c...rdinal&rhsyns=
binary 0/1 is a special case of more general 0/1/2,... models
when using multi or ordinal you will have automatic simulation and vpc
you can also write your LL + simulate statement to do whatever you need
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