How does one calculate within NCA the PK parameter AUCt-INF (AUC from time last extrapolated to infinity)?
Thanks for your help!
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Posted 13 September 2022 - 02:08 PM
I would use the simple calculation of AUCinf-AUCtz
You can do this in a data wizard or in Phoenix 8.1 onwards using the the "user defined parameters" in the NCA object itself, see below;
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