I have a PKPD model where I use a dosing to start a PD challenge (I dose the "effect" into an ODE).
As the experiment is spanning multiple doses and weeks. I would like to display the results in TAD. My problem is that the time resets after both drug dosing and effect dosing.
Can I set the TAD to be after the drug dosing only OR could I input an effect into the effect compartment with the use of a sequence statement at the times defined by a flag in my dataset. Instead of using a dosing statement.
Like: (or something like that)
fcovariate(effectDose)
sequence{E=effectDose}
BR Frederik
PS I can't send you the file.