Dear All,
During an analysis I encountered a case when AUC0-24, which was extrapolated since the last measurable observation was around 4 h, was (very slightly) larger than AUCinf_pred:
- AUC024: 1.314578765489
- AUCinf_pred: 1.314034376517
- AUCinf_obs: 1.314654951761
I played around with the partial AUCs to figure out what could have happened and I think it is related to the difference between Clast and Clast_pred.
Interestingly however, during my investigation, when I tried to approximate AUCinf with partial areas using extremely big "End Time" values (100000000 h), I started to get very strange results. The AUC suddenly became much larger, which I cannot explain. Is this an expected behaviour somehow?
Thanks,
Marta
Attached Files
Edited by rosame, 19 January 2023 - 04:18 PM.