I can find information on how to perform a nonparametric analysis of Tmax for cross-over studies in WNL, but is it also possible to perform a nonparametric analysis of Tmax for a single sequence study in WNL?
I have a single sequence Drug-Drug interaction study and I would like to perform a nonparametric analysis of Tmax in WNL, but I am not sure if that is possible.
The single sequence is like this:
On Day 1 Compound X is administered and on Day 5 Compound X is administered together with a moderate CYP3A4 inhibitor in steady-state.
Can I statistically compare Tmax (Compound X) of Day 5 vs Day 1 using nonparametric analysis in WNL?
Kind regards,
Mark