2 replies to this topic

[Davidq8]

Hi,

 

I want to use FFM instead of body weight for allometric scaling, but I'm not sure if setting the impact to 1 for VD and 0.75 for CL is correct with FFM.

 

Aslo, can we still use body weight as a covariate after implementing the FFM effect?

 

 

Thanks 

 

 

 

[smouksassi1]

https://bpspubs.onli....1111/bcp.14202please look at this publication.

you can still look at other size covariates to see if there is any residual effects 

[Davidq8]

Thanks for your answer, Sameer !!

The study is very interesting and helpful to clarify the concept.