1 reply to this topic

[Davidq8]

Hello, I am working on a model, and I need to test the model with plasma concentration to be log-transformed.

Is there an option in the software to transform drug exposure data from normal scale to log scale, or should it be done first before uploading the dataset?

Also, How can I transform estimated PK parameters back to normal scale after the analysis using the software?

 

[Ana Henry]

Hello, I am working on a model, and I need to test the model with plasma concentration to be log-transformed.

Is there an option in the software to transform drug exposure data from normal scale to log scale, or should it be done first before uploading the dataset?

Also, How can I transform estimated PK parameters back to normal scale after the analysis using the software?

The best option is to use a data wizard - add a transformation and select the type 'functions'. There you can create a column that is the log of the original concentration or take the exponential of a value.  Please see attached screenshot.

 

Ana Henry

Certara University

Attached Thumbnails

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