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[peggy.lin@effpha.com]

Hi all,

 

I came across a paper describing a method for estimating the time to steady state analysis in SAS (see the attachment). One of the methods, NOSTASOT (stepwise test of linear trend), can be executed using the Linear Mixed Effects model in WinNonlin (WNL). In WNL, there are "Contrasts" and "Estimates" tabs; however, I am unsure how to use these tabs to perform the analysis in the same way SAS does.

 

Does anyone have experience assessing the time to steady state using WNL?

 

Thanks,

Peggy

 

Attached Files

•  Estimating Time to Steady State Analysis in SAS.pdf   436.56KB   2 downloads