Dear All,
I am using the design like RR,RT1,RT2,T1T2,T1T1,T2T2 and objective is to find the ICV for R,T1 and T2,. Due to time constraints we can not go for higher period design.
After running BE wizard I have got the following from Final varince Parameter sheet:
Dependent Units Parameter Estimate
Ln(AUCt) lambda(1,1)_11 0.452901932
Ln(AUCt) lambda(1,2)_11 0.467542526
Ln(AUCt) lambda(1,3)_11 0.544891068
Ln(AUCt) lambda(2,2)_11 5.36705E-07
Ln(AUCt) lambda(2,3)_11 2.88626E-07
Ln(AUCt) Var(Period*For*Subject)_21 0.03710071
Ln(AUCt) Var(Period*For*Subject)_22 0.038877323
Ln(AUCt) Var(Period*For*Subject)_23 0.03240041
So can any one tell me how to estimate ICV for R,T1 and T2 from Winnonlin.
Thanks in advance
Best Regards
Ashwani