Dear Serge,
Thank you for your prompt reply after such a long flight.
Actually the urine data is amount in urine. Sorry for the confusion. So I revised your model (delete S1; use amount instead of concentration;use the actual dose; add Fe) and it worked perfectly (please see the attachment).
But I still have some questions:
1) In your model, the green box CObsurine is an continuous block and the Curine white box is an expression box for input? For each obs block added, there must be an input expression for it? I do not see an expression block for CObs.
2) A silly question. I can insert an observation box and an expression box but can not connect them. How to connect them just like you did in your model?
Thank you very much!
LLLi
Dear LLLI
Originally I had to define an expression to get the urine concentration because you gave me cumulative concentrations in rine which of course do not make any sense. The urine compartment is in amount and the observation was in concentration. Therefore you cannot connect amount with concentration.
Therefore an expression was needed to define the response in the same units as the observation.
Then you could connect the predicted response with he observed response which is what is needed.
Now that the response is in amount, you can link directly the A0 compt with the observation which is what I did in the attached project.
I get the same answer and all is good.
You can connect an expression to an observation. This is what I did.
I do not understand. Pu the cursor on the expression until you see Aurine , left click , keep the mouse pushed and drag to the observation box where you see written Curine and release the mouse.
Best
Serge