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Error 14062

deconvolve UIR

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#1 RosyMtz

RosyMtz

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Posted 14 September 2016 - 05:52 PM

Hi, 
 
I hope you can help me, for my IVIVC I have two formulations: Prueba and Referencia, for both i have in vivo data and in vitro data, then i have in vivo data of  IR formulation, but when i try to run, WNL doesn`t generate UIR and doesn`t deconvolve the data. After that appears the following errors:
 
 
Validation observed baseline NCA. Warning and errors:
 
Formulation=Prueba
ERROR: 14062: Duplicate time values on data file. Use Descriptive Statistics to compute mean data and perform NCA on the means, or select Sparse Sampling in NCA.
 
 
See Core Output for more details
 
No final parameters generated. See text output for more details
 
 
Vivo.UIR Menas. Warning and errors:
 
Formulation=IR, sujeto=p2
Error occurred in processing.  See ASCII output file.
*** ERROR 10203 *** AN ERROR OCCURRED DURING CURVE STRIPPING.
*** ERROR 10201 *** INITIAL ESTIMATES CANNOT BE DETERMINED FOR THIS MODEL.
 
this for each subjet.

Edited by RosyMtz, 14 September 2016 - 05:52 PM.


#2 bwendt@certara.com

bwendt@certara.com

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Posted 14 September 2016 - 06:00 PM

Hi Rosy,

 

the error message indicates a problem with your data. Can you share your project file so that we can take a closer look? If you prefer you may want to send it to support@certara.com

 

Bernd







Also tagged with one or more of these keywords: deconvolve, UIR

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