I am trying to simultaneously model a drug and its metabolite (PK19 in Dr. Dan Weiner's book).
There are totally 3 dose levels (300, 50 and 10 mg iv infusion in 5 min). This model is supposed to include a 2-compartment drug model with Michaelis-Menten elimination that provides the formation of the metabolite, and a 1-compartment metabolite model.
I first used a graphical 2-compartment iv infusion model and then added another central compartment for metabolite. Please see more detail in the project attached. After I click the execute bottom, I got a warning message saying
"Could not merge sort times