Hi all,
I have a subject with unknown concentration at 72h and I want to calculate the AUC0-72.
Which method I should to employ in this subject?
Method 1) Partial area calculation where t0=0h and t72=72
Method 2) Based on topics that I've seen in this forum: Estimate the concentration at 72h by the expression in attached image "conc" and then apply the formula to calculate AUC given by the expression in attached image "auc".
Method 3) There is another method?
The results obtained by method 1 and 2 are a little different....it is normal?
Thanks for the support,
Best regards,
Mariana