Drug development based on the information obtained from the central workshop physiological pharmacokinetic (PBPK ) Model

This event runs from 1st – 5th August 2016 in Tokyo, Japan

By participating in this workshop, you can learn how to predict the following items.
Drug metabolic clearance (CL) Drug interactions was through the metabolism · (DDIs)
The first pass in the gastrointestinal tract And absorption after oral administration (including the effects of diet and dosage forms)
Pharmacokinetics and DDI impact of transporters and intestines liver ring against
Distribution of the drug to the various tissues -Individual differences in drug blood concentration transition in a certain population
Specific population (children, race, various diseases) the difference in the body dynamics in · Various drug pharmacodynamic (PD) And plasma concentrations remained consistent with the measured value of the clinical trial (parameter identification (use of IVIVE and PBPK in PE)

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