I just sent out a ticket to Certara support but later found this useful forum on technical discussions on Pirana and other Certara products.
When I tried to test use of bootstrap in pirana, per the instruction, I click on model diagnosis then bootstrap, used the default command:
bootstrap -samples=50 -threads=4 -dir=bs_run6 run6.mod
(run6.mod is my control file. It is actually the control PK file that Pirana founder Ron Keizer used for ACOP training back to a few years ago. with the data file as acop.csv.)
It immediately gave me an error:
fatal error: cannot open file: '50/bootstrap.r' no such file or directory
I can run psn for VPC or NPC successfully but not bootstrap, suggesting installation of Pirana seems fine. Wonder what happen to my installation. I googled but could not find that bootstrap.r is needed for Pirana.
It may be just a no-brainer question thus appreciate anyone familiar with Pirana can help on this.