Hi all,
I’m working on a 3 period, 3 treatment, crossover PK study; using the bioequivalence module to determine BE (Test/Reference) (Test/Comparator) I’m able to execute the run where I have an equal number of observations per treatment. Where I have an uneven number, LSMs are not estimable and I receive the error message: "ERROR 11016: Numerical problem when computing satterthwaite df."
I suspect the issue/answer is within the information above but if anyone could shed any light on this, I’d be very grateful.
Thanks in advance,
Danielle