Nonlinear Clearance
October 6, 2016 | 10am EST
Presenter: Dan Weiner
https://support.cert...earance/?p=3921
Metabolite Kinetics
Simultaneously model plasma data of a drug and a metabolite following 5-minute infusion. Metabolite clearance follows Michaelis-Menten kinetics
October 20, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...inetics/?p=3986
Two-compartment Repeated Oral Dosing
Fit multiple dose kinetic and dynamic data sequentially
November 3, 2016 | 10am EST
Presenter: Bernd Wendt
https://support.cert...-dosing/?p=4051
Nonlinear Kinetics
Fit nonlinear clearance for a highly plasma-bound compound using Michaelis-Menten elimination for two subjects with different Km
November 17, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...builder/?p=4188
Simultaneous Fitting of IV/PO Data
Fit IV data first then IV and PO data separately and simultaneously
December 1, 2016 | 10am EST
Presenter: Bernd Wendt
https://support.cert...ne-data/?p=4229
Target-Mediated Drug Disposition
Model circulating plasma target with a TMDD model
December 15, 2016 | 10am EST
Presenter: Dan Weiner
https://support.cert...osition/?p=4250
Enterohepatic Recirculation
Model enterohepatic recirculation (EHC) after intravenous administration
January 19, 2017 | 10am EST
Presenter: Bernd Wendt
https://support.cert...ulation/?p=4340
One-compartment 1st and 0-order Input
Fit and discriminate between first and zero-order absorption models
February 2, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...r-input/?p=4365
Allometry-Elementary/Complex Dedrick Plot
Simultaneously fit an allometric model to data from mouse, rat and man
February 16, 2017 | 10am EST
Presenter: Dan Weiner
https://support.cert...scaling/?p=4412
Turnover III: Nonlinear Disposition
Characterize turnover of an endogenous compound
March 2, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...osition/?p=4432
Analysis and Comparison of Link, Turnover and Receptor Binding Models
Fit a link-, turnover- and receptor binding model to data
March 16, 2017 | 10am EST
Presenter: Dan Weiner
https://support.cert...g-model/?p=4463
Sigmoidal Concentration-response Models
Apply Gompertz, Weibull, Richards, Morgan-Mercer-Flodin, Hill and logistic models
March 30, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...-models/?p=4488
Analysis of a Tissue Growth/Kill Model
Analyze a tumor cell kill model after acute dosing
April 13, 2017 | 10am EST
Presenter: Bernd Wendt
https://support.cert...wthkill/?p=4499
Modeling Inhibition of Enzyme Activity by Means of Turnover
Construction of a mechanistic turnover model
April 27, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...urnover/?p=4508
Effect Compartment III: IV infusion
Model response-time data with a link-model
May 11, 2017 | 10am EST
Presenter: Dan Weiner
https://support.cert...nfusion/?p=4516
Turnover Model 1: IV Bolus Dosing
Model Warfarin-PCA interaction
June 8, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...r-model/?p=4561
Turnover Model 4: IV Infusions
Apply a turnover model to multiple IV dosing response data
June 22, 2017 | 10am EST
Presenter: Bernd Wendt
https://support.cert...nfusion/?p=4573
Turnover Model 1: Repeated Dosing I
Apply a turnover model to repeated po dosing response data
July 13, 2017 | 10am EST
Presenter: Chris Mehl
https://support.cert...-dosing/?p=4611
Dose-response-time Analysis I-IV
Analyze dose-response-time data with an instantenous effect model
July 27, 2017 | 10am EST
Presenter: Bernd Wendt
https://support.cert...nalysis/?p=4656
Transduction Modeling: Assessment of Number of Transit Compartments
Analyze a transduction rate limited response time course
August 10, 2017 | 10am EST
Presenter: Bernd Wendt
https://support.cert...odeling/?p=4679
Minimal physiologically-based pharmacokinetic model for monoclonal antibodies
November 16 | 10 am EST
Presenter: Loan Pharm (Camargo)
https://support.cert...ibodies/?p=4875
Target-mediated Drug Disposition (TMDD) modeling using the Quasi-equilibrium assumption
November 30 |10 am EST
Presenter: Frank Striebel (Morphosys)
https://support.cert...umption/?p=4896
Adaptive Simulations: extending PML to trial simulations
December 14 | 10 am EST
Presenter: Bernd Wendt (Certara)
https://support.cert...lations/?p=4909
Edited by bwendt@certara.com, 05 August 2020 - 12:17 PM.
