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Linear Mixed Effects Model Estimates

Linear Mixed Effects Model Phoenix WinNonlin

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#1 littlepetinga



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Posted 06 April 2021 - 11:49 AM

Hello All,


I am using Phoenix WinNonlin 8.2 Linear Mixed Effects Model tool to identify differences between a Treatment and Placebo.


On the Final Fixed Parameters output, I noticed that the program is calculating the estimate,  CI and p-value for Placebo, and that for Treatment those appear as 'Not estimable'.


I ask if it's possible to define the variable (e.g., Treatment instead of Placebo) for which the program will calculate the estimates.


Thank you in advance


#2 bwendt@certara.com


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Posted 14 April 2021 - 08:39 AM

Dear Sara,


in principal, you have an input with a column where you specify your Treatment:




You would then use this column (Treatment) as variable in your model specification:




Please refer to our LinMix example that you find in your Phoenix installation.




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