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Phoenix NLME Model Warnings


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#1 ElliotOffman

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Posted 17 March 2015 - 04:29 PM

I get the following set of errors pretty frequently with the model I'm trying to run. its a PBPK model I coded and its worked prior, but I've made a change recently to estimate a specific new parameter and now getting all sorts of errors...clearly Phoenix does not appreciate my model.

anyway, any help in understanding what these errors mean may help me diagnose my error. thank you!

Elliot

 

 

Error in Population:
Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\14988 registry key, error 5, Access is denied.

Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\8932 registry key, error 5, Access is denied.

Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\10704 registry key, error 5, Access is denied.

Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\6268 registry key, error 5, Access is denied.

Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\8532 registry key, error 5, Access is denied.

Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\11536 registry key, error 5, Access is denied.

Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\8580 registry key, error 5, Access is denied.

Unable to open the HKEY_LOCAL_MACHINE\SOFTWARE\MPICH\SMPD\process\4404 registry key, error 5, Access is denied.

iMethod = 6
 Eng 6 process 2 of  8 is alive
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc
 sigmaLchol=  0.133705
 Initial fcntheta1 value  196.909897
 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1
 DLSODE-  At T (=R1) and step size H (=R2), the                                 
       corrector convergence failed repeatedly                                  
       or with ABS(H) = HMIN                                                    
      In above,  R1 =  0.2101419299838E+01   R2 =  0.3172448663666E-15
 DLSODE-  ISTATE (=I1) illegal                                                  
      In above message,  I1 =        -5
 DLSODE-  Run aborted.. apparent infinite loop                                  
iMethod = 6
 Eng 6 process 1 of  8 is alive
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc
 sigmaLchol=  0.133705
 Initial fcntheta1 value  196.909897
 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1
 DLSODE-  At T (=R1) and step size H (=R2), the                                 
       corrector convergence failed repeatedly                                  
       or with ABS(H) = HMIN                                                    
      In above,  R1 =  0.2101418427349E+01   R2 =  0.1307332705062E-14
 DLSODE-  ISTATE (=I1) illegal                                                  
      In above message,  I1 =        -5
 DLSODE-  Run aborted.. apparent infinite loop                                  
unable to read the cmd header on the pmi context, Error = -1
.
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
SuspendThread failed with error 5 for process 1:045B29C7-CA32-4e37-9432-023DDF5D97D6:'mpiNLME7.exe @nlmeargs.txt /e -1 cols1.txt data1.txt out000001.txt'
unable to suspend process.
unable to read the cmd header on the pmi context, Error = -1
.
iMethod = 6
 Eng 6 process 0 of  8 is alive
 entering naive pooled engine 6, iteration limit= 1000
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 

 READFLAGS
 environmental flags and variables
 0 iflagnp
 0 iflagrestart
 1 norderAGQ
 1 iflagfocehess
 1 iflagverbose
 1 Allow Gaussian Fit
 1 METHODblup
 10 NDIGITblup
 1 METHODlagl
 13 NDIGITlagl
 1 iflagIEXP
  0.00200000009 tolmodlinz
 0 nrep_pcwres
 500 Nsample
 200 Nburn
 0 iflaganagrad
 1 iodelevelused
 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc

 Initial thetas and bounds
    i      Thetalo(i)      Thetainit(i)                 Thetahi(i)
    1     -0.1000+101      0.1000E-02      0.1000+101
    2      0.1000E-02      0.1337E+00      0.1000+101
 sigmaLchol=  0.133705

 initial packed param vector and typx vector
         i        packed(i)        typx(i)
         1        0.001000        0.001000
         2        0.133705        0.133705

 Initial fcntheta1 value  196.909897

 Nsub from initxtheta= 3
 Nobstotal =  41

 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
unable to read the cmd header on the pmi context, Error = -1
.
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
received kill command for a pmi context that doesn't exist: unmatched id = 6
unable to read the cmd header on the pmi context, Error = -1
.
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
iMethod = 6
 Eng 6 process 3 of  8 is alive
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc
 sigmaLchol=  0.133705
 Initial fcntheta1 value  196.909897
 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1
unable to read the cmd header on the pmi context, Error = -1
.
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
iMethod = 6
 Eng 6 process 4 of  8 is alive
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc
 sigmaLchol=  0.133705
 Initial fcntheta1 value  196.909897
 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1
unable to read the cmd header on the pmi context, Error = -1
.
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
iMethod = 6
 Eng 6 process 5 of  8 is alive
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc
 sigmaLchol=  0.133705
 Initial fcntheta1 value  196.909897
 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1
unable to read the cmd header on the pmi context, Error = -1
.
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
iMethod = 6
 Eng 6 process 6 of  8 is alive
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc
 sigmaLchol=  0.133705
 Initial fcntheta1 value  196.909897
 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1
unable to read the cmd header on the pmi context, Error = -1
.
Error posting readv, An existing connection was forcibly closed by the remote host.(10054)
iMethod = 6
 Eng 6 process 7 of  8 is alive
 Starting Engine  6

 Problem dimensions

 Nsub =     3
 getntheta()= 2
 getnsigma()= 0
 lenEta =   0
 lenSigma =  1

 NorderAGQ not applicable to this engine  6
 NorderAGQ set to 1 but unchanged in nlmeflags.asc
 sigmaLchol=  0.133705
 Initial fcntheta1 value  196.909897
 corresponding ELSobj with zeroed blups=  318.466834

 Starting -loglikelihood =  196.909897

 optimizing thetas, iteration= 1

job aborted:
rank: node: exit code[: error message]
0: RMTL2438PK17AF7.celerion.local: 123
1: RMTL2438PK17AF7.celerion.local: 0: process 1 exited without calling finalize
2: RMTL2438PK17AF7.celerion.local: 0: process 2 exited without calling finalize
3: RMTL2438PK17AF7.celerion.local: 123
4: RMTL2438PK17AF7.celerion.local: 123
5: RMTL2438PK17AF7.celerion.local: 123
6: RMTL2438PK17AF7.celerion.local: 123
7: RMTL2438PK17AF7.celerion.local: 123
Error: Exception: Fortran Exception

NlmeErrorExit: close files and exit(0)

Error: Exception: Fortran Exception

NlmeErrorExit: close files and exit(0)

 

Model execution failed or cancelled



#2 smouksassi1

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Posted 20 March 2015 - 05:21 PM

It will be good to revert back to the working code and then do your changes step by step to see where the code breaks.

Elliot thank you for sharing the project. It seems the model runs when Max ODE is matrix exponent but not in stiff.
Indeed the model is stiff and we might not have enough data to support it.

Another avenue is trying to tweak some of the advanced parameters in the engine:

like ODE rel Tol Abs Tol or max step. This really problem dependent.






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