..In that case, the file use for the NCA cannot be used for plotting the full conc-time profile of each subject (one plot with all doses and PK) as i guess you need to duplicate the row with the last conc following a given dose (the last conc of Dose N is also the predose Dose N+1 but if you sort with Dose for NCA, then time of dosing of Dose N+1 cannot be the time of Dose N). Ed
Again without seeing your actual data file and your reporting protocol needs it's not possible to say for sure, but remember that in Phoenix you can indeed create extra columns using e.g. the Data Wizard to hold a continuous time from first dose as well as time relative to last dose.
if you need to create extra rows i.e. so that Day 2, 0h also exists as Day 1, 24h then this is a data management issue that has existed at least 20 years, again you can do it in Phoenix, however I would really recommend that your data supplier takes responsibility to create this record for you, (same sample has two 'PK' identities), with some flag to indicate the sample record is duplicated if required.
Simon.