Jump to content


Choose different residual error structure

residual error

  • Please log in to reply
1 reply to this topic

#1 LLLi


    Advanced Member

  • Members
  • PipPipPip
  • 92 posts

Posted 13 October 2016 - 02:49 PM

Hi all,


I fitted a 2 compartment model to a set of data (only one subject) using different residual error structures. Please see the phoenix project attached.


I compared the Ind DV vs IPRED; lnd DV, IPRED vs IVAR (y is logarithmic scale); lnd IWRES vs IPRED; and Ind IWRES vs IVAR. I also gave a score to each structure for each figure (score 1 means the best, score 3 means the worst). Please see the excel attached. Which residual error structure is the best one?


Thank you!



Attached Files

#2 Simon Davis

Simon Davis

    Advanced Member

  • Administrators
  • 1,175 posts

Posted 13 October 2016 - 03:28 PM

I would personally go with mixed, it has the lowest AIC of the 3 models and generally the best residual plots.


I suggest you take another look at Ind IWRES vs IPRED, since for mixed there are no points outside the 2 sd lines and generally are closer to the centre line than additive or indeed multiplicatve alone



Also tagged with one or more of these keywords: residual error

0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users