In this link, advice is provided wrt. how to adjust for unequal variances when doing BE testing in parallel design.
There are two "parallel testing" examples in the PHX flow, and it is stated that both columns Repeated and Period may be used . However, the two columns are not similar - one has the all 1's (Period) and one has 1-2, suggesting that each subject gets the both treatments.
I can see that results are the same for the approaches, but I dont understand why that is?
Secondly, I have used the approach in a study with 3 treatments Ref-Test1-Test2. Test 1 is not of relevance for me, however I get two different results if I analyse BE of Test 2 vs. Ref on the data with and with Test 1 excluded from the datasheet. How do the data from Test 1 inform the analysis and should it be included or not? THX