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Integration for AUC in PML model


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#21 Bertold Renner

Bertold Renner

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Posted 08 November 2011 - 11:54 AM

Jason,

 

Many thanks for your help! I understand the 10% difference, now.

I have tried both of your suggestions and found the second version to be more appropriate in my case.

 

Thank you

 

Bertold



#22 mippolito@jhu.edu

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Posted 22 May 2019 - 08:33 PM

I would like to derive AUC as a secondary parameter from a pop PK model but the code included in this thread is not recognized in the current NLME build e.g. secondary(AUC = AaDose/tvV/tvKe). Is there anybody out there who can please provide the updated code? Thank you.



#23 Simon Davis

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Posted 23 May 2019 - 07:16 AM

If this no longer valid, then it suggests that you have changed one of the built-in models and then it will depend on what changes you made as to what the valid formula would be.  If you are in text mode you can simply  use;

deriv(AUCx=C)

 

more options like partial AUCs are described on the forum before e.g. earlier in this actual thread and also here;

 

https://support.cert...rameter/?p=1639

 

 Simon


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