1 reply to this topic

[raghava choudary]

Hi all,

 

Can anybody help in obtaining a best fit to the data. The compound follows non-linear PK.

 

with best regards,

 

R

 

 Plasma PK Modeling_Nonlinear.phxproj   1.32MB   541 downloads

[Simon Davis]

Hi Raghav, I looked at your project and it seemed that you just had to refine your initial estimates and then you need to assess your model.  I have done this for you, of the models I tried i believe 2 com with multiplicative error is best on balance; if you look at the model comparer you can se i thas the lowest AIC and generally the best residual plots.  To learn more about model fitting and selection why not take one of our online courses e.g.;

 

 

http://www.certarauniversity.com/lms/index.php?r=course/details&id=26

 

  Simon.

Attached Files

•  Plasma PK Modeling_Nonlinear_v64.phxproj   3.52MB   530 downloads