This is a PK 1 compartment IV infusion model fit using First Order Conditional Estimation (FOCE). Body weight is included as a covariate in a linear relationship for volume.
For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.
NONMEM to NLME Translation PK 1comp IV infusion covariate.pdf 1.51MB 37 downloads
1Comp_IV_infusion_covariate.phxproj 1.08MB 28 downloads