Jump to content


Photo

PK 1 Compartment IV Infusion Covariate

NONMEM PML IV Infusion Covariate

  • Please log in to reply
No replies to this topic

#1 bwendt@certara.com

bwendt@certara.com

    Advanced Member

  • Administrators
  • 188 posts

Posted 01 December 2017 - 08:55 AM

This is a PK 1 compartment IV infusion model fit using First Order Conditional Estimation (FOCE). Body weight is included as a covariate in a linear relationship for volume.

For model translation information, refer to the attached slide deck. The model is run in both NLME and NONMEM in the attached Phoenix project file.

 

Attached File  NONMEM to NLME Translation PK 1comp IV infusion covariate.pdf   1.51MB   37 downloads

 

Attached File  1Comp_IV_infusion_covariate.phxproj   1.08MB   28 downloads







Also tagged with one or more of these keywords: NONMEM, PML, IV, Infusion, Covariate

0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users